Comparison of Effects Antibiotics and Natural Honey and Extracts of Plants on Escherichia coli Growth Isolated from Different Pathogenic Cases

Authors

  • Amal Talib AL-Sa'ady Dept. Clinical Laboratory Sciences, College of Pharmacy, University of Babylon, Hillah, Iraq
  • Yasser Haider Al-Mawla DNA Research Center, University of Babylon, Hillah, Iraq

Keywords:

Escherichia coli, Plant extracts, Alcoholic Extract, honey extract

Abstract

This study included four aspects:

Collection of 200 samples of patients with four different pathogenic cases: Burns infections, Wound infections, Urinary Tract Infections & diarrhea , for period ( September 2016 – March2017) . 403 bacterial isolates were got. Gram negative bacteria represented  329  isolates (48.9%  E.coli ). The percentages of E.coli  isolates  are different depending on isolation sources and the Urinary Tract Infections have the highest (72.2%).

Antibiotic Susceptibility test was performed for 10  antibiotics, all isolates of  E.coli  showed perfect resistance against  Penicillins & Cephalosporins while they have high sensitivity to Nitrofurantion . The other  6 antibiotics have different effects depending on the isolation sources.

Natural Honey has potential high ability for  E.coli  growth inhibiting without any influence with isolation sources , MIC of Ntural Honey is  15%.

The inhibition activity was tested for Ethanol (95%) Extracts of four Medicinal plants : Allium sativum , Paganum harmala , Nigella sativum & Myrtus communs . All of these extracts have high inhibitory effect on  E.coli  isolates without any influence of the isolation sources. Allium sativum extract has the highest effect with inhibition zone diameters (20.1-32.0) mm.

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Published

2019-08-01

How to Cite

[1]
A. T. . AL-Sa’ady and Y. H. . Al-Mawla, “Comparison of Effects Antibiotics and Natural Honey and Extracts of Plants on Escherichia coli Growth Isolated from Different Pathogenic Cases”, JUBPAS, vol. 27, no. 3, pp. 420-34, Aug. 2019.

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Articles