Preparation, Characterization of A New Cis – Iodoplatin and Cis - Carboplatin Complexes and Study There Spectral, Physical and Pharmaceutical Properties

Abstract

This search includes preparation of new cis–platin, in the form of iodin, and new two cis - carboplatin complexes {cis  [Pt(4-aminoantipyrine) (NH₃)₂]I₂ and cis[Pt (aminosalicylicacid) (NH₃)₂]I},   which used as anti - cancer drugs, they are prepared by using the organic ligands 4-amino salicylic acid and 4-amino anti pyrine. These complexes were characterized by using UV–Vis., FTIR, XRD and ¹HNMR spectroscopic techniques . The effect of the concentration and the temperature on the molar electrical conductivity of its solutions were studied. The expiry date (half-life) for the solutions of the complexes in the circumstances at the degrees (35⁰C) and (20 ⁰C) was determined